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	Provedor de dados BJMBR (1) BJM (1) Autor Chen,Yan (2) Chen,Yu (1) Wang,Jianfeng (1) Wang,Jinjun (1) Wu,Liyan (1) Xu,Liqun (1) Zheng,Yu (1) Zhou,Zhihong (1) Mais... Palavra-chave Acinetobacter pittii (1) Anti-inflammatory effects (1) Baicalein (1) BlaOXA-357 (1) Lipopolysaccharide (1) MAPK pathway (1) Multidrug-resistance (1) NF-κB pathway (1) Tubular-interstitial nephritis (1) Whole genome sequencing (WGS) (1) Mais... Tipo do documento Info:eu-repo/semantics/article (2) Ano 2018 (1) 2017 (1) País Brazil (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Baicalein alleviates tubular-interstitial nephritis in vivo and in vitro by down-regulating NF-κB and MAPK pathways BJMBR Chen,Yan; Zheng,Yu; Zhou,Zhihong; Wang,Jinjun. Tubular-interstitial nephritis (TIN) is characterized by tubular cell damage and inflammatory lesions of kidneys. Baicalein (BAI) is a flavonoid compound found in the roots of Scutellaria baicalensis Georgi. The present study was undertaken to explore the anti-inflammatory and anti-oxidative effects of BAI on TIN patients and a lipopolysaccharide (LPS)-induced TIN cell model. The expression levels of interleukin-6 (IL-6), IL-10, and tumor necrosis factor α in serum samples of TIN patients and culture supernatants of renal proximal tubular epithelial cells (RPTECs) were evaluated using enzyme-linked immunosorbent assay. Creatinine clearance was calculated using the Cockcroft-Gault equation. Activities of malondialdehyde, superoxide dismutase, and... Tipo: Info:eu-repo/semantics/article Palavras-chave: Tubular-interstitial nephritis; Baicalein; Lipopolysaccharide; Anti-inflammatory effects; NF-κB pathway; MAPK pathway. Ano: 2018 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2018001000606 Draft genome sequence of a multidrug-resistant beta-lactamase OXA-357-producing Acinetobacter pittii ST865 clinical isolate from China BJM Wang,Jianfeng; Chen,Yan; Wu,Liyan; Chen,Yu; Xu,Liqun. Abstract Worldwide increasing emergence of carbapenem-resistant Acinetobacter spp. has rendered the limited availability of effective antimicrobial agents and has become a major public health concern. In this study, we report the draft genome sequence of A. pittii TCM156, a multidrug-resistant isolate that harbored the blaOXA-357 gene. The genome sequence was further analyzed by various bioinformatics methods. The genome size was estimated to be 3,807,313 bp with 3508 predicted coding regions and G + C content is 38.7%. These findings have raised awareness of the possible emergence of OXA-type enzyme-producing A. pittii isolate in China. Tipo: Info:eu-repo/semantics/article Palavras-chave: Acinetobacter pittii; BlaOXA-357; Whole genome sequencing (WGS); Multidrug-resistance. Ano: 2017 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822017000200196 Registros recuperados: 2 Primeira ... 1 ... Última

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